Kernicterus is a rare but serious complication of untreated jaundice in babies. It's caused by excess bilirubin damaging the brain or central nervous system.
In newborn babies with very high levels of bilirubin in the blood (hyperbilirubinaemia), the bilirubin can cross the thin layer of tissue that separates the brain and blood (the blood-brain barrier).
The bilirubin can damage the brain and spinal cord, which can be life threatening.
Brain damage caused by high levels of bilirubin is also called bilirubin encephalopathy.
Your baby may be at risk of developing kernicterus if:
Kernicterus is now very rare in the UK, affecting less than 1 in every 100,000 babies.
Initial symptoms of kernicterus in babies include:
As kernicterus progresses, additional symptoms can include fits (seizures) and muscle spasms that can cause arching of the back and neck.
Treatment for kernicterus involves using an exchange transfusion as used in the treatment of newborn jaundice.
If significant brain damage occurs before treatment, a child can develop serious and permanent problems, such as: