How and when to take steroid tablets
Take your medicine as instructed by your doctor. They'll explain how much to take and how often.
It's normally best to take steroid tablets with or soon after a meal – usually breakfast – because this can stop them irritating your stomach.
If you miss a dose or take too much
If you forget a dose, take it as soon as you remember. If it's almost time for your next dose, skip the one you missed.
Do not take a double dose to make up for a forgotten dose.
Accidentally taking too many steroid tablets is unlikely to be harmful if it's a one-off. Speak to your doctor or a pharmacist if you're worried.
Taking too many steroid tablets over a long period can make you more likely to get side effects.
Coming off treatment
Do not stop taking your medicine without talking to your doctor.
If you've been taking steroid tablets for more than a few days, you usually need to reduce your dose gradually. Stopping suddenly can cause your adrenal gland, which makes important hormones for the body, to stop working. This is known as adrenal insufficiency.
Symptoms of adrenal insufficiency include:
- feeling extremely tired
- feeling and being sick
- loss of appetite and weight loss
Your original symptoms may also come back suddenly.
Your doctor will be able to provide more advice about how to safely stop taking steroids.
Side effects of steroid tablets
Taking steroid tablets for less than 3 weeks is unlikely to cause any significant side effects. But you may get some side effects if you need to take them for longer or at a high dose.
Side effects of steroid tablets can include:
- indigestion or heartburn
- increased appetite, which could lead to weight gain
- difficulty sleeping
- changes in mood and behaviour, such as feeling irritable or anxious
- an increased risk of infections – especially chickenpox, shingles and measles
- high blood sugar or diabetes
- weakening of the bones (osteoporosis)
- high blood pressure
- Cushing's syndrome – which can cause symptoms such as thin skin that bruises easily, a build-up of fat on the neck and shoulders and a red, puffy, rounded face
- eye conditions, such as glaucoma and cataracts
- mental health problems, such as depression or suicidal thoughts; get an urgent GP appointment or call 111 if this happens
Most side effects will pass once treatment stops. Tell your doctor if they bother you.
You can report any suspected side effect to the UK Yellow Card safety scheme.
Coping with side effects of steroid tablets
The following tips may help reduce the side effects of steroid tablets:
- take your tablets in the morning with breakfast (although some specially coated tablets can be taken without food) – this may help prevent indigestion, heartburn and sleeping difficulties
- eat a healthy, balanced diet and exercise regularly – this may help prevent weight gain and osteoporosis
- avoid close contact with people who are ill; especially people who have measles, chickenpox or shingles – get medical advice as soon as possible if you think you may have been exposed to someone with an infection
- ensure your vaccines are up-to-date – but do not have any "live" vaccines, such as the shingles vaccine
Your doctor may reduce your dose or suggest taking your tablets less often (for example, every other day) if you're having side effects.
They may also sometimes recommend other medicines to take alongside steroids to protect you from some of the side effects, such as medicines to help prevent indigestion or heartburn, or medicines that help strengthen the bones.
You may be given a special steroid treatment card that explains how you can reduce the risk of side effects.
Taking steroid tablets with other medicines, food or alcohol
Some medicines interfere with the way steroid tablets work. Tell your doctor if you take any other medicines, including herbal remedies and supplements, before starting steroid tablets.
If you're already taking steroid tablets, ask your doctor or a pharmacist for advice before taking any other medicines, remedies or supplements.
You can usually drink alcohol while taking steroid tablets, but do not drink too much as this may irritate your stomach.
You can also eat most foods while taking steroid tablets. Do not eat liquorice while taking prednisolone, however, as this can increase the amount of the medicine in your body.
Who can take steroid tablets
Most people can take steroid tablets.
Tell your doctor before starting treatment if you:
- have had an allergic reaction to steroids in the past
- have an infection (including eye infections)
- you have recently had, or are about to have, any vaccinations
- have an open wound that has not healed yet
- are pregnant, breastfeeding or trying for a baby
- have any other conditions, such as diabetes, epilepsy, high blood pressure, or problems with your liver, heart or kidneys
Steroid tablets may not be suitable in these cases, although your doctor may recommend them if they think the benefits outweigh any risks.
Steroid tablets are not usually recommended for children as they can cause growth problems.
How steroid tablets work
Steroids are a manmade version of hormones normally produced by the adrenal glands, which are 2 small glands found above the kidneys.
When taken in doses higher than the amount your body normally produces, steroids reduce redness and swelling (inflammation). This can help with inflammatory conditions such as asthma and eczema.
Steroids also reduce the activity of the immune system, the body's natural defence against illness and infection.
Steroid tablets are different from the anabolic steroids used illegally by some people to increase their muscle mass.